Mexico City + Yucatán · Travel Medicine
Tacos at midnight in Roma. Ceviche at noon in Tulum. The bag rule for both.
Get azithromycin, dicyclomine, and ondansetron prescribed before you fly. Ready at your pharmacy in under 24 hours — three Rx that turn Montezuma's revenge into a half-day inconvenience instead of a lost trip.
- Physician-founded
- Licensed in all 50 states
- HSA / FSA eligible
- Same-day Rx in most cases
A two-city Mexico itinerary runs on food the way a Patagonia trek runs on weather. Centro Histórico tlacoyos, Coyoacán market lunches, the late-night al-pastor circuit in Roma and Condesa, then south to Mérida, Valladolid, and a Tulum stretch built around cenote swims and beachside ceviche. The CDC ranks traveler's diarrhea as the single most common illness on trips to Mexico, with 30 to 70 percent of travelers reporting at least one episode on a 2-week trip through Latin America. The combination travelers actually need is not just the antibiotic — it is the antibiotic plus something for the cramping and something for the nausea, packed before the first taco. The right three prescriptions in your bag mean a bad ceviche becomes one slow morning on the hotel patio, not a Tulum urgent-care that does not take your US insurance.
Mexico travel health guide — vaccines, snapshot overview, and what to review before you go.
Orders are reviewed and prescriptions sent to your pharmacy within 24 hours.
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+1 (302) 251-2302Rx at your pharmacy in three steps.
No appointment. No waiting room. Answer a few questions and a licensed provider reviews within hours.
Your destination, dates, health history, and current medications. Takes about 2 minutes.
A licensed clinician reviews your health profile, checks for interactions, and approves your prescription.
- Allergy screen passed
- Drug interactions clear
- Prescription approved
Your approved prescription is sent electronically to the pharmacy of your choice. Pick it up when your pharmacy has it ready.
Skip the appointment. Get the same Rx.
Both columns cover the visit and prescribing only. Your pharmacy bills the medication itself on either side.
Medications in the Mexico City & Yucatán plan
Mexico medication FAQ
- Most travelers will not need them, but the CDC ranks traveler's diarrhea as the single most common illness on trips to Mexico, with 30 to 70 percent of travelers on 2-week Latin America itineraries reporting at least one episode. The CDMX + Yucatán circuit hits both ends of that range — street food in Roma and Coyoacán, market lunches in Mérida, beachside ceviche in Tulum, and cenote day-trips where the snack bar is whatever the local vendor packed. Having the prescriptions in your bag before you fly means a bad meal becomes one slow morning on the hotel patio instead of a hunt for a Tulum urgent-care that does not take your US insurance.
- Take 500 mg by mouth once daily for 3 days, starting at the first signs of significant diarrhea (typically 3 or more loose stools in 24 hours, or any diarrhea with fever, blood, or severe cramping). Most travelers feel better within 24 hours of the first dose. Take with water, with or without food. If the cramping is severe before the antibiotic kicks in, the dicyclomine in the Travel Pack handles that; if you cannot keep water down, the ondansetron dissolves on your tongue.
- Three prescriptions in one visit. Azithromycin 500 mg, taken once daily for 3 days, to treat bacterial traveler's diarrhea — the CDC first-line for Latin America. Dicyclomine (Bentyl), an antispasmodic for the abdominal cramping that pairs with the antibiotic course; useful for the doubled-over period before the azithromycin kicks in. And ondansetron (Zofran) dissolving tablets for nausea and vomiting from any cause, including heat, mild altitude on arrival in Mexico City, or a bad-batch ceviche on a Tulum beach day. Three risks, three prescriptions, one visit.
- Probably not in the textbook sense. Mexico City sits at 7,350 ft (2,240 m), just below the 2,500 m / 8,200 ft threshold the CDC uses to flag acute mountain sickness risk. Most sea-level travelers feel a little short of breath on day one, especially walking up stairs in Centro or hiking Chapultepec, but full-blown AMS is rare at this elevation. If you are stacking CDMX with a high-altitude leg — Nevado de Toluca, the volcanoes near Puebla, or a Tepoztlán hike — that is a separate altitude conversation. For the standard CDMX + Yucatán trip, no Diamox needed. The ondansetron in the Travel Pack handles the mild nausea some travelers feel from the elevation on arrival.
- Not for Mexico City or the Yucatán peninsula. The CDC restricts malaria prophylaxis recommendations in Mexico to specific rural areas of Chiapas, Oaxaca, Tabasco, and a handful of other states — not the destinations covered in this brief. Mexico City, Cancún, Playa del Carmen, Tulum, Mérida, Valladolid, and the standard cenote / Chichén Itzá circuit are outside the malaria-risk zone. If your trip extends to rural Chiapas or southern Oaxaca, talk to your provider — that is a different prescription conversation.
- Dengue is a real risk on the Yucatán peninsula, particularly in the warm-wet months (June through November) and in the coastal towns. There is no prescription that prevents dengue — prevention is mosquito-bite avoidance: EPA-registered repellent (DEET 20 to 30 percent), long sleeves at dawn and dusk, and air-conditioned or screened rooms. If you develop fever within 2 weeks of returning from Mexico, see a doctor and tell them where you traveled. Wandr's medications treat the bacterial and heat-related problems you can actually pre-prescribe for — dengue is not one of them.
- If a provider can't safely prescribe (rare, usually due to a contraindication), the visit fee is refunded in full. You only pay if the Rx is sent.
Eat the street food. Pack the prescriptions for when it eats back.
One visit, three prescriptions for the Mexico TD trifecta — antibiotic, antispasmodic, anti-nausea. Reviewed by a US-licensed provider, ready at your pharmacy before you fly.