Petra & Wadi Rum · Travel Medicine
Jordan is malaria-free. The Middle East still tops CDC's TD list.
Get azithromycin before you fly to Amman. 500 mg once a day for three days, taken on demand the moment traveler's diarrhea hits. CDC's first-line choice for Jordan. Ready at your pharmacy before you leave.
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Petra, Wadi Rum, Amman, and Aqaba are all explicitly malaria-free per CDC — Malarone is not part of this trip. What the same CDC pages flag is the food and water risk. CDC's Yellow Book groups the Middle East with Africa as the highest-risk region for traveler's diarrhea, with attack rates of 30 to 70 percent over a typical two-week trip. That risk plays out exactly where a Jordan itinerary spends its time: Amman souk meals, Wadi Musa hotel buffets at the base of Petra, Bedouin camp dinners under the stars in Wadi Rum, and the Dead Sea resort buffets on the way back north. Azithromycin is CDC's first-line empiric antibiotic. One tablet, once a day, for three days — taken on demand the moment TD hits.
Jordan travel health guide — vaccines, snapshot overview, and what to review before you go.
Orders are reviewed and prescriptions sent to your pharmacy within 24 hours.
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+1 (302) 251-2302Rx at your pharmacy in three steps.
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Your destination, dates, health history, and current medications. Takes about 2 minutes.
A licensed clinician reviews your health profile, checks for interactions, and approves your prescription.
- Allergy screen passed
- Drug interactions clear
- Prescription approved
Your approved prescription is sent electronically to the pharmacy of your choice. Pick it up when your pharmacy has it ready.
Skip the appointment. Get the same Rx.
Both columns cover the visit and prescribing only. Your pharmacy bills the medication itself on either side.
Medications in the Petra & Wadi Rum plan
Petra & Wadi Rum medication FAQ
- No. CDC explicitly states malaria is not a concern in Jordan and that medication to prevent infection is not necessary for any region of Jordan, including Amman, Aqaba, Petra, or Wadi Rum. The right travel-medicine play for a Jordan itinerary is not Malarone — it's traveler's diarrhea coverage on demand. If you're chaining Jordan with a country that does have malaria (a Nile cruise extension into Upper Egypt, parts of sub-Saharan Africa), that's a separate conversation for a separate brief.
- CDC's Yellow Book groups the Middle East alongside Africa as the highest-risk region for traveler's diarrhea, with attack rates of 30 to 70 percent over a typical two-week trip. That's the upper end of the global range — well above the 8 to 20 percent rate CDC assigns to intermediate-risk destinations like South Africa or parts of the Caribbean. The risk concentrates exactly where a Jordan itinerary spends its time: souk meals in Amman, Wadi Musa hotel buffets at the base of Petra, Bedouin camp dinners in Wadi Rum, and the resort buffets along the Dead Sea. Having azithromycin already in your bag means a bad meal becomes a one-day setback instead of three days in your hotel room.
- On demand, not prophylactically. The CDC standard is to start a three-day course at the first sign of moderate-to-severe traveler's diarrhea — defined as diarrhea bad enough that it interferes with your planned activities, or any diarrhea that turns bloody, is paired with fever, or persists past 24 hours. One 500 mg tablet once a day for three days. Stick to bottled water in Jordan (the standard precaution per CDC), use the common-sense food rules, and break out azithromycin if TD breaks through.
- Three prescriptions in one visit. Azithromycin 500 mg once daily for three days for empiric traveler's diarrhea treatment across Amman, Petra, Wadi Rum, and the Dead Sea. Ondansetron orally dissolving tablets for breakthrough nausea, covering both TD-driven vomiting and the heat-driven nausea that hits on the 850-step Monastery climb or in a 4x4 Wadi Rum tour when the dunes top 40°C in summer. Prescription-strength ibuprofen for the Monastery (Ad-Deir) climb, the Treasury-to-High-Place-of-Sacrifice loop, the all-day Wadi Rum jeep tours that pound the lower back, and the general heat-and-walking fatigue of the southern Jordan circuit. One visit, three prescriptions, the actual risk profile of this itinerary.
- CDC recommends both typhoid and hepatitis A vaccination for travelers to Jordan because both are spread through contaminated food and water. Hepatitis A is a shot given at a travel clinic, pharmacy, or your primary-care office. Typhoid can be the same kind of shot, or the oral vaccine (Vivotif), which a Wandr physician can prescribe online; the capsules need to be finished at least a week before you fly. This brief covers the prescription side of your trip: empiric treatment for the TD attack rate CDC flags as highest-tier for the Middle East, plus the bundle add-ons that match the actual itinerary. Confirm vaccination status against the latest CDC Jordan page well before you fly.
- Summer (June through August) regularly hits 40°C / 104°F in both Petra and Wadi Rum, with no shade on the Monastery hike and limited shade in Wadi Rum's open desert. Hydration is the primary defense — carry more water than you think you need, start the Monastery climb at the 6 a.m. site opening, and plan Wadi Rum 4x4 tours for sunrise or late afternoon rather than midday. Ondansetron in the Travel Pack covers the breakthrough nausea that can come with heat stress; ibuprofen Rx covers the headache and aches. Neither replaces basic heat-management common sense.
- Orders are reviewed by a US-licensed provider and the Rx is sent electronically to your pharmacy within 24 hours. Most travelers can pick it up the same day.
- If a provider can't safely prescribe (rare, usually due to a contraindication or drug interaction), the visit fee is refunded in full. You only pay if the Rx is sent.
Walk the Siq with the antibiotic that actually fits the risk.
Azithromycin before you fly. Ondansetron and Rx-strength ibuprofen in the pack for the Monastery climb and the Wadi Rum heat. Reviewed by a US-licensed provider, ready at your pharmacy in under 24 hours.