Traveler's Diarrhea

Azithromycin (Traveler's Diarrhea)

Oral tablet · 1 treatment course

Azithromycin is a broad-spectrum antibiotic and the CDC's first-line recommendation for traveler's diarrhea in South and Southeast Asia, where fluoroquinolone resistance is prevalent. Through Wandr Health, a treatment course is available from $89 with no appointment needed. No appointment needed.

Overview

Traveler's diarrhea affects 30–70% of international travelers (CDC). Azithromycin targets the most common bacterial causes — Campylobacter, enterotoxigenic E. coli (ETEC), and Shigella — and is the CDC's preferred first-line option for South and Southeast Asia, where fluoroquinolone resistance is high.

Typically taken as a single 1,000 mg dose or 500 mg daily for 3 days. The CDC recommends self-treatment when diarrhea is incapacitating or accompanied by fever or bloody stools. Having a course on hand lets you begin treatment immediately.

Sources: CDC Yellow Book 2026; FDA prescribing information

Wandr Health vs. a traditional travel clinic

Wandr Health
Travel Clinic
Provider visit$89+$200+
Your timeUnder 10 minutesHours in a waiting room
AppointmentNone neededRequired
Follow-upUnlimited messagingNew appointment

Other travel medications

When travelers use this

  • Trips to South and Southeast Asia where fluoroquinolone resistance is common
  • Travelers who need a broad-spectrum option effective against Campylobacter
  • Those with fluoroquinolone allergies or contraindications
  • Backpackers and long-term travelers in high-risk regions like India and Nepal

Compare with Ciprofloxacin

Ciprofloxacin is the CDC's preferred option for most destinations outside South and Southeast Asia where fluoroquinolone resistance is low.

View Ciprofloxacin

Related guides

Antibiotic stewardship

Wandr Health follows CDC guidelines for responsible antibiotic prescribing. All antibiotic prescriptions are reviewed by a licensed provider who evaluates appropriateness based on your destination and health profile.

Read our stewardship policy →

Frequently asked questions

Medical disclaimer
This page is for educational and informational purposes only and does not constitute medical advice. All treatment decisions are made by a licensed provider based on your individual health profile.
$89
Provider visit · Rx sent to your pharmacy
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Answer a few health questions. A licensed provider reviews and recommends treatment.
Licensed provider review included
Same-day pharmacy pickup
HSA/FSA eligible
Unlimited provider messaging
How it works
1
Answer a few questions about your trip
2
A provider reviews and recommends treatment
3
If prescribed, it's sent to a pharmacy near you
Questions?
Our care team can help with travel medication questions.
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Medically reviewed by the Wandr Health Medical Team · Last updated March 30, 2026
Same-day reviewFully onlineHIPAA compliant
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