Nausea & Vomiting

Ondansetron (Nausea & Vomiting)

Oral tablet (ODT) · 30 tablets

Ondansetron (generic Zofran) is a prescription antiemetic widely prescribed for travelers prone to motion sickness, food poisoning–related nausea, or vomiting from other travel illnesses. Through Wandr Health, 30 tablets are available for $44 — no appointment needed. No appointment needed.

Overview

Ondansetron blocks serotonin (5-HT3) receptors that trigger the vomiting reflex. Available as an orally disintegrating tablet (ODT) that dissolves on the tongue without water — ideal when active nausea makes swallowing pills difficult.

Commonly co-prescribed alongside antibiotics for traveler's diarrhea. Use with caution in individuals with heart rhythm disorders (QT prolongation).

Sources: CDC Yellow Book 2026; FDA prescribing information

Wandr Health vs. a traditional travel clinic

Wandr Health
Travel Clinic
Provider visit$89+$200+
Your timeUnder 10 minutesHours in a waiting room
AppointmentNone neededRequired
Follow-upUnlimited messagingNew appointment

Other travel medications

When travelers use this

  • Travelers experiencing nausea from food, altitude, or motion during trips
  • As a companion medication during traveler's diarrhea treatment
  • Anyone with a history of travel-related nausea who wants a fast-acting option

Related guides

Frequently asked questions

Medical disclaimer
This page is for educational and informational purposes only and does not constitute medical advice. All treatment decisions are made by a licensed provider based on your individual health profile.
$89
Provider visit · Rx sent to your pharmacy
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Answer a few health questions. A licensed provider reviews and recommends treatment.
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Unlimited provider messaging
How it works
1
Answer a few questions about your trip
2
A provider reviews and recommends treatment
3
If prescribed, it's sent to a pharmacy near you
Questions?
Our care team can help with travel medication questions.
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Medically reviewed by the Wandr Health Medical Team · Last updated March 30, 2026
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