Traveler's Diarrhea

Ciprofloxacin (Traveler's Diarrhea)

Oral tablet · 1 treatment course
Reviewed by Wandr Health Medical TeamUpdated March 2026

Ciprofloxacin is a fluoroquinolone antibiotic and one of the CDC's recommended options for self-treatment of traveler's diarrhea acquired in most regions outside South and Southeast Asia. Through Wandr Health, a treatment course is available for $74 with free shipping. No appointment needed.

Overview

Traveler's diarrhea affects 30–70% of international travelers (CDC). Ciprofloxacin is effective against the most common bacterial causes including enterotoxigenic E. coli, Salmonella, and Shigella. It remains the CDC's primary recommendation for most destinations outside South/Southeast Asia.

It is typically used as a single 750 mg dose or 500 mg twice daily for 1–3 days. The CDC recommends self-treatment when diarrhea is incapacitating or accompanied by fever or bloody stools. Having a course on hand allows travelers to begin treatment immediately.

The CDC notes that fluoroquinolone resistance is increasing in South and Southeast Asia, where Azithromycin is preferred. For all other destinations — including Africa, Central/South America, and the Middle East — Ciprofloxacin remains a first-line option.

Sources: CDC Yellow Book 2026; FDA prescribing information

Wandr Health vs. a traditional travel clinic

Wandr Health
Travel Clinic
Medication cost$74$50–$120+
Professional fee$25 (flat)$75–$150
Total estimated$99$125–$270+
AppointmentNone neededRequired
ShippingFree (3–5 days)Pharmacy pickup
Follow-upUnlimited messagingNew appointment

Other travel medications

Frequently asked questions

Medical disclaimer
This page is for educational and informational purposes only and does not constitute medical advice. All treatment decisions are made by a licensed provider based on your individual health profile.
Traveler's Diarrhea
Ciprofloxacin
Oral tablet · 1 treatment course
$74
+ $25 professional fee · Free shipping
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