Anxiety & Jetlag
Hydroxyzine (Anxiety & Jetlag)
Oral tablet · 30 tablets
Hydroxyzine is a prescription antihistamine used to manage travel anxiety, flight anxiety, and jet lag–related insomnia. Unlike benzodiazepines, it carries no risk of dependence. Through Wandr Health, 30 tablets are available from $89. No appointment needed.
Overview
Hydroxyzine is a non-habit-forming antihistamine that produces mild anxiolytic and sedative effects without the addiction risk of benzodiazepines. Commonly taken at 25–50 mg, 30–60 minutes before a flight or at bedtime for jet lag adjustment.
Drowsiness is the most common side effect — often beneficial for overnight flights or jet lag recovery. Unlike controlled substances, Hydroxyzine carries no travel restrictions across international borders.
Sources: FDA prescribing information; clinical practice guidelines
Wandr Health vs. a traditional travel clinic
Wandr Health
Travel Clinic
Provider visit$89+$200+
Your timeUnder 10 minutesHours in a waiting room
AppointmentNone neededRequired
Follow-upUnlimited messagingNew appointment
Other travel medications
When travelers use this
- Travelers with pre-flight or travel-related anxiety
- Managing jetlag-related sleep disruption on long-haul trips
- Allergic reactions to new environments, foods, or insect bites while abroad
Related guides
Frequently asked questions
Medical disclaimer
This page is for educational and informational purposes only and does not constitute medical advice. All treatment decisions are made by a licensed provider based on your individual health profile.
$89
Provider visit · Rx sent to your pharmacy
Get StartedAnswer a few health questions. A licensed provider reviews and recommends treatment.
✓Licensed provider review included
✓Same-day pharmacy pickup
✓HSA/FSA eligible
✓Unlimited provider messaging
How it works
1
Answer a few questions about your trip
2
A provider reviews and recommends treatment
3
If prescribed, it's sent to a pharmacy near you
Medically reviewed by the Wandr Health Medical Team · Last updated March 30, 2026
Same-day reviewFully onlineHIPAA compliant
Get Started