Dicyclomine (Abdominal Cramps)

Overview

Abdominal cramping is one of the most debilitating symptoms of traveler's diarrhea and other food- or water-borne illnesses encountered abroad. While antibiotics address the underlying infection, the cramping itself can persist and significantly impair travel plans. Dicyclomine (generic Bentyl) works by relaxing the smooth muscle of the gastrointestinal tract, reducing spasms and associated pain.

As an anticholinergic antispasmodic, Dicyclomine specifically targets the muscarinic receptors in the gut wall, decreasing both the tone and motility of smooth muscle. This provides rapid relief from cramping without directly affecting the course of infection, making it an effective complement to antibiotic therapy.

For travelers to regions with high rates of enteric illness — including South and Southeast Asia, sub-Saharan Africa, and parts of Latin America — carrying Dicyclomine alongside a prescribed antibiotic ensures comprehensive management of traveler's diarrhea symptoms. It is typically taken on an as-needed basis, 3–4 times daily for acute episodes.

Wandr Health vs. a traditional travel clinic

Other travel medications

Frequently asked questions